Synthesis, anticonvulsant screening, and molecular modeling studies of new arylalkylimidazole oxime ether derivatives
Sign Up to like & getrecommendations! Published in 2019 at "Drug Development Research"
DOI: 10.1002/ddr.21491
Abstract: In this study, 15 new oxime ether derivatives were synthesized and their anticonvulsant activities were screened in vivo. The compounds were synthesized by the reaction of various alkyl halides with 1‐(2‐naphthyl)‐2‐(1H‐imidazol‐1‐yl)ethanone oxime. Their anticonvulsant activities… read more here.
Keywords: oxime; anticonvulsant screening; oxime ether; synthesis anticonvulsant ... See more keywords
Design, Synthesis, and Fungicidal Activities of Novel Piperazine Thiazole Derivatives Containing Oxime Ether or Oxime Ester Moieties.
Sign Up to like & getrecommendations! Published in 2023 at "Pest management science"
DOI: 10.1002/ps.7374
Abstract: BACKGROUND To study the effect of changing the piperidine ring of oxathiapiprolin on the fungicidal activity, we designed and synthesized novel piperazine thiazole derivatives containing oxime ether or oxime ester moieties, and studied their fungicidal… read more here.
Keywords: oxime ester; oxime ether; fungicidal activities;
Oxime Ether Lipids as Transfection Agents: Assembly and Complexation with siRNA.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7138-1_16
Abstract: RNAi-based therapeutic approaches to combat cancer and other diseases are currently an area of great interest. However, practical applications of this approach rely on optimal tools to carry and deliver siRNA to the desired site.… read more here.
Keywords: ether lipids; oxime ether; sirna delivery; lipids transfection ... See more keywords
Oxime Ether Synthesis through O-H Functionalization of Oximes with Diazo Esters under Blue LED Irradiation.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c02555
Abstract: A green and sustainable oxime ether formation method via the visible-light-promoted O-H functionalization of oximes with diazo esters is described. The reaction occurs under very mild conditions (catalyst- and additive-free) with a high yield and… read more here.
Keywords: functionalization oximes; oxime ether; diazo esters; ether synthesis ... See more keywords
Polytopal Rearrangement Governing Stereochemistry of Bicyclic Oxime Ether Synthesis
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DOI: 10.3390/ijms232012331
Abstract: In the present study, four O-substituted oximes of quinuclidin-3-one were synthesized using appropriate O-substituted hydroxylamine hydrochlorides. In order to perform these reactions in a solvent, a mixture of (E) and (Z) products was yielded. Using… read more here.
Keywords: oxime ether; synthesis; governing stereochemistry; stereochemistry ... See more keywords
Novel Fluorinated 7-Hydroxycoumarin Derivatives Containing an Oxime Ether Moiety: Design, Synthesis, Crystal Structure and Biological Evaluation
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DOI: 10.3390/molecules26020372
Abstract: A series of fluorinated 7-hydroxycoumarin derivatives containing an oxime ether moiety have been designed, synthesized and evaluated for their antifungal activity. All the target compounds were determined by 1H-NMR, 13C-NMR, FTIR and HR-MS spectra. The… read more here.
Keywords: fluorinated hydroxycoumarin; oxime ether; derivatives containing; ether moiety ... See more keywords