Synthesis of cholera toxin B subunit glycoconjugates using site-specific orthogonal oxime and sortase ligation reactions
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DOI: 10.3389/fchem.2022.958272
Abstract: The chemoenzymatic synthesis of a series of dual N- and C-terminal–functionalized cholera toxin B subunit (CTB) glycoconjugates is described. Mucin 1 peptides bearing different levels of Tn antigen glycosylation [MUC1(Tn)] were prepared via solid-phase peptide… read more here.
Keywords: cholera toxin; ligation; oxime sortase; toxin subunit ... See more keywords