The Oxindole GW-5074 Inhibits JC Polyomavirus Infection and Spread by Antagonizing the MAPK-ERK Signaling Pathway
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DOI: 10.1128/mbio.03583-22
Abstract: Human polyomaviruses, such as JCPyV and BKPyV, cause significant morbidity and mortality in immunocompromised or immunomodulated patients. There are no treatments for polyomavirus-induced diseases other than restoration of immune function. We discovered that the oxindole… read more here.
Keywords: oxindole 5074; jcpyv bkpyv; infection; polyomavirus induced ... See more keywords