Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro‐Oxindole Dihydroquinazolinones as IRAP Inhibitors
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DOI: 10.1002/open.201900344
Abstract: Abstract Insulin‐regulated aminopeptidase (IRAP) is a new potential macromolecular target for drugs aimed for treatment of cognitive disorders. Inhibition of IRAP by angiotensin IV (Ang IV) improves the memory and learning in rats. The majority… read more here.
Keywords: oxindole dihydroquinazolinones; irap inhibitors; evaluation proposed; irap ... See more keywords