LIGHT is increased in patients with coronary disease and regulates inflammatory response and lipid metabolism in oxLDL-induced THP-1 macrophages.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.06.110
Abstract: Inflammation is critical for the progression of hyperlipidemia. Although the exact mechanism through which inflammation affects hyperlipidemia is not very clear, evidence suggests that the tumor necrosis factor superfamily member 14 (TNFSF14/LIGHT)LIGHT might regulate lipid… read more here.
Keywords: coronary disease; thp macrophages; induced thp; oxldl induced ... See more keywords
MiR-32-5p/AIDA Mediates OxLDL-Induced Endothelial Injury and Inflammation.
Sign Up to like & getrecommendations! Published in 2022 at "International heart journal"
DOI: 10.1536/ihj.22-067
Abstract: The role of endothelial injury and inflammation in atherosclerosis has been well established. miRNAs have been found to be key regulators in the development of atherosclerosis. Here we investigated whether miR-32-5p and its predicted target… read more here.
Keywords: endothelial injury; mir; injury inflammation; oxldl induced ... See more keywords
Rosmarinic acid downregulates the oxLDL-induced interaction between monocytes and endothelial cells, in addition to monocyte diapedesis, under high glucose conditions
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2022.5125
Abstract: Endothelial dysfunction during diabetes has been previously reported to be at least in part attributed to increased oxidized low-density lipoprotein (oxLDL) levels mediated by high glucose (HG) levels. Endothelial inflammation increases the adhesiveness of monocytes… read more here.
Keywords: oxldl induced; addition; adhesion; rosmarinic acid ... See more keywords
Protective Effect of N-Acetylcysteine (NAC) on oxLDL-Induced Endothelial Dysfunction
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Microbiology and Biotechnology"
DOI: 10.4014/jmb.2504.04039
Abstract: N-acetylcysteine (NAC), a well-known antioxidant and glutathione precursor, has been extensively studied for its free radical-scavenging properties, anti-inflammatory effects, and ability to enhance cellular redox balance. NAC has also been shown to mitigate oxidative damage… read more here.
Keywords: oxldl induced; nac; endothelial dysfunction; induced endothelial ... See more keywords