3-(2-(2-Oxo-2H-chromene-3-carbonyl)hydrazono)-N-(pyridin-2-yl)butanamide Complexes: Synthesis, Characterization, DFT, Biological, and Ion-flotation studies
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Heterocyclic Chemistry"
DOI: 10.1002/jhet.2990
Abstract: Schiff base complexes of Cu(II), Ni(II), Cd(II), and Zn(II) with 3-(2-(2-oxo-2H-chromene-3-carbonyl)hydrazono)-N-(pyridin-2-yl)butanamide (H2L) were produced. The synthesized compounds were deduced by elemental analysis, molar conductance, magnetic susceptibility, and spectroscopic techniques. The geometry of the prepared complexes… read more here.
Keywords: oxo chromene; chromene carbonyl; hydrazono pyridin; pyridin butanamide ... See more keywords
Synthesis and investigation of anti-inflammatory and anticonvulsant activities of novel coumarin-diacylated hydrazide derivatives
Sign Up to like & getrecommendations! Published in 2020 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2020.10.034
Abstract: Abstract A number of novel coumarin derivatives synthesized by the reaction of 3-carbonyl chloride coumarin with some substituted aryl acid hydrazides to investigate their anti-inflammatory and anticonvulsant activities. Carrageenan (0.1 ml of 1%, w/v) was… read more here.
Keywords: anti inflammatory; novel coumarin; anticonvulsant activities; oxo chromene ... See more keywords
Cytotoxicity of 4-hydroxy-N-(naphthalen-1-yl)-2-oxo-2H-chromene-3-carboxamide in multidrug-resistant cancer cells through activation of PERK/eIF2α/ATF4 pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2021.114788
Abstract: After decades of research, multidrug resistance (MDR) remains a huge challenge in cancer treatment. In this study, the cytotoxic of 4-hydroxy-N-(naphthalen-1-yl)-2-oxo-2H-chromene-3-carboxamide (MCC1734) has been investigated towards multidrug-resistant cancer cell lines. MCC1734 exerted cytotoxicity on cell… read more here.
Keywords: naphthalen oxo; oxo chromene; chromene carboxamide; multidrug resistant ... See more keywords