Development of a background signal suppression probe for 8-oxoguanine DNA glycosylase detection.
Sign Up to like & getrecommendations! Published in 2021 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2021.338741
Abstract: 8-oxoguanine DNA glycosylase (OGG), which plays a crucial role in base excision repair (BER), is an important biomarker. The existing highly sensitive fluorescent methods always need complicated amplification design. The method with high sensitivity and… read more here.
Keywords: oxoguanine dna; background signal; dna glycosylase; probe ... See more keywords
The activity of the DNA repair enzyme hOGG1 can be directly modulated by ubiquinol.
Sign Up to like & getrecommendations! Published in 2020 at "DNA repair"
DOI: 10.1016/j.dnarep.2019.102784
Abstract: The DNA of human cells suffers about 1.000-100.000 oxidative lesions per day. One of the most common defects in this category is represented by 7,8-dihydro-8-oxoguanine. There are numerous exogenous effects on DNA that induce the… read more here.
Keywords: oxoguanine dna; activity; dna glycosylase; dna ... See more keywords
A ratiometric electrochemical assay for human 8-oxoguanine DNA glycosylase amplified by hybridization chain reaction
Sign Up to like & getrecommendations! Published in 2019 at "Electrochemistry Communications"
DOI: 10.1016/j.elecom.2019.05.006
Abstract: Abstract Human 8-oxoguanine DNA glycosylase 1 (hOGG1) is an important DNA repair enzyme, which is closely related to the occurrence and development of certain diseases. Ultrasensitive and accurate detection of hOGG1 is significant for fundamental… read more here.
Keywords: oxoguanine dna; dna; dna glycosylase; ratiometric electrochemical ... See more keywords