Articles with "oxphos dependency" as a keyword



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Drugging OXPHOS Dependency in Cancer.

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Published in 2019 at "Cancer discovery"

DOI: 10.1158/2159-8290.cd-nd2019-005

Abstract: Researchers at The University of Texas MD Anderson Cancer Center in Houston are developing an inhibitor of oxidative phosphorylation, IACS-10759, that targets complex I of the mitochondrial electron transport chain. Ongoing early clinical studies indicate… read more here.

Keywords: dependency cancer; oxphos dependency; cancer; drugging oxphos ... See more keywords