Articles with "oxr1 antagonism" as a keyword



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The role of orexin-1 receptor signaling in demand for the opioid fentanyl

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Published in 2019 at "Neuropsychopharmacology"

DOI: 10.1038/s41386-019-0420-x

Abstract: The orexin system is a potential treatment target for drug addiction. Orexin-1 receptor (OxR1) antagonism reduces demand for cocaine and remifentanil, indicating that orexin-based therapies may reduce demand for many classes of abused drugs. However,… read more here.

Keywords: orexin; opioid fentanyl; oxr1 antagonism; orexin receptor ... See more keywords