OXTR DNA methylation moderates the developmental calibration of neural reward sensitivity.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental psychobiology"
DOI: 10.1002/dev.22026
Abstract: The Adaptive Calibration Model of Stress Responsivity (ACM) suggests that developmental experiences predictably tune biological systems to meet the demands of the environment. Particularly important is the calibration of reward systems. Using a longitudinal sample… read more here.
Keywords: oxtr dna; methylation; calibration; reward ... See more keywords
Oxytocin receptor gene (OXTR) DNA methylation is associated with autism and related social traits – A systematic review
Sign Up to like & getrecommendations! Published in 2021 at "Research in Autism Spectrum Disorders"
DOI: 10.1016/j.rasd.2021.101785
Abstract: Abstract There is emerging evidence implicating oxytocin receptor gene (OXTR) DNA methylation (DNAm) in social behaviour. This review investigated its association with autism spectrum disorder (ASD) characteristics and related social dimensions, both in individuals with… read more here.
Keywords: gene oxtr; receptor gene; autism; dna methylation ... See more keywords
Genetic and epigenetic modulation of the oxytocin receptor and implications for autism
Sign Up to like & getrecommendations! Published in 2020 at "Neuropsychopharmacology"
DOI: 10.1038/s41386-020-00832-3
Abstract: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social communication impairments and repetitive behaviors that result from genetic and epigenetic factors. Three decades of research have demonstrated that the oxytocin system is a… read more here.
Keywords: oxtr dna; methylation; brain; genetic epigenetic ... See more keywords