Selective synthesis of enol ethers via nickel-catalyzed cross coupling of α-oxy-vinylsulfones with alkylzinc reagents.
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DOI: 10.1039/d1cc05347g
Abstract: We describe here a Ni-catalyzed Negishi coupling reaction to prepare 1,2-dialkyl enol ethers in a stereoconvergent fashion. This method employs readily available and bench-stable α-oxy-vinylsulfones as electrophiles. The C-sulfone bond in the α-oxy-vinylsulfone motif is… read more here.
Keywords: enol ethers; oxy vinylsulfones; selective synthesis; cross coupling ... See more keywords