Copper-Catalyzed Three-Component Reaction of Alkynes, TMSN3, and Ethers: Regiocontrollable Synthesis of N1- and N2-Oxyalkylated 1,2,3-Triazoles.
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DOI: 10.1021/acs.orglett.9b02295
Abstract: A new copper-catalyzed selective synthesis of N1- and N2-oxyalkylated 1,2,3-triazoles has been developed through a three-component reaction of alkynes, TMSN3, and ethers. Through this methodology, a series of N1- and N2-oxyalkylated 1,2,3-triazoles could be efficiently… read more here.
Keywords: reaction alkynes; synthesis oxyalkylated; three component; oxyalkylated triazoles ... See more keywords