Role of orbitofrontal cortex in incubation of oxycodone craving in male rats
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DOI: 10.1111/adb.12927
Abstract: One of the main challenges in treating opioid‐use disorders is relapse during abstinence, triggered by re‐exposure to drug‐associated cues. Previous studies have demonstrated that drug‐seeking in rats progressively increases over time during withdrawal (incubation of… read more here.
Keywords: oxycodone craving; ofc; incubation; withdrawal day ... See more keywords
GluA2‐lacking AMPA receptors in the nucleus accumbens core and shell contribute to the incubation of oxycodone craving in male rats
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DOI: 10.1111/adb.13237
Abstract: One of the most challenging issues in the treatment of substance use disorder, including misuse of opioids such as oxycodone, is persistent vulnerability to relapse, often triggered by cues or contexts previously associated with drug… read more here.
Keywords: core shell; oxycodone craving; incubation oxycodone; male rats ... See more keywords
Incubation of Oxycodone Craving Following Adult-Onset and Adolescent-Onset Oxycodone Self-Administration in Male Rats
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2021.697509
Abstract: Relapse is a major obstacle to curb the ongoing epidemic of prescription opioid abuse. We and others previously demonstrated that oxycodone seeking in adult rats progressively increases after abstinence from oxycodone self-administration (incubation of oxycodone… read more here.
Keywords: self administration; adult; oxycodone craving; oxycodone self ... See more keywords