Oxygen‐Generating Cryogels Restore T Cell Mediated Cytotoxicity in Hypoxic Tumors
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202102234
Abstract: Solid tumors are protected from antitumor immune responses due to their hypoxic microenvironments. Weakening hypoxia‐driven immunosuppression by hyperoxic breathing of 60% oxygen has shown to be effective in unleashing antitumor immune cells against solid tumors.… read more here.
Keywords: cell mediated; generating cryogels; hypoxic tumors; oxygen generating ... See more keywords
Preservation of Blood Vessels with an Oxygen Generating Composite
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DOI: 10.1002/adhm.201701338
Abstract: Damage caused by oxygen deficiency (hypoxia) is one of the major factors limiting tissue and organ preservation time. Cooling tissues slows down metabolic rate of cells thereby prolonging tissue and organ survival sufficiently to allow… read more here.
Keywords: preservation blood; preservation; oxygen generating; blood ... See more keywords
Methods for Incorporating Oxygen-Generating Biomaterials into Cell Culture and Microcapsule Systems.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6364-5_10
Abstract: A major obstacle to long-term performance of tissue construct implants in regenerative medicine is the inherent hypoxia to which cells in the engineered construct are exposed prior to vascularization of the implant. Various approaches are… read more here.
Keywords: methods incorporating; cell culture; incorporating oxygen; oxygen generating ... See more keywords
A hybrid oxygen-generating wound dressing based on chitosan thermosensitive hydrogel and decellularized amniotic membrane.
Sign Up to like & getrecommendations! Published in 2022 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2021.119020
Abstract: Amniotic membrane (AM) has been utilized as a wound dressing extensively. Given the importance of oxygen in wound healing, here we have reported the fabrication and characterization of an oxygen-generating wound dressing based on AM.… read more here.
Keywords: generating wound; wound dressing; oxygen; amniotic membrane ... See more keywords
Oxygen-Generating Biomaterials for Translational Bone Regenerative Engineering.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c20715
Abstract: Successful regeneration of critical-size defects remains one of the significant challenges in regenerative engineering. These large-scale bone defects are difficult to regenerate and are often reconstructed with matrices that do not provide adequate oxygen levels… read more here.
Keywords: regenerative engineering; bone; bone regenerative; oxygen ... See more keywords
Harnessing the potential of oxygen-generating materials and their utilization in organ-specific delivery of oxygen.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d2bm01329k
Abstract: The limited availability of transplantable organs hinders the success of patient treatment through organ transplantation. In addition, there are challenges with immune rejection and the risk of disease transmission when receiving organs from other individuals.… read more here.
Keywords: organ specific; harnessing potential; generating materials; oxygen ... See more keywords
Engineered algae: A novel oxygen-generating system for effective treatment of hypoxic cancer
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.aba5996
Abstract: Engineered living microalgae can relieve tumor hypoxia in situ and sensitize tumor cells to radiation and photodynamic therapies. Microalgae, a naturally present unicellular microorganism, can undergo light photosynthesis and have been used in biofuels, nutrition,… read more here.
Keywords: oxygen; microalgae; treatment; oxygen generating ... See more keywords
Electrospraying Oxygen-Generating Microparticles for Tissue Engineering Applications
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s237334
Abstract: Background The facile preparation of oxygen-generating microparticles (M) consisting of Polycaprolactone (PCL), Pluronic F-127, and calcium peroxide (CPO) (PCL-F-CPO-M) fabricated through an electrospraying process is disclosed. The biological study confirmed the positive impact from the… read more here.
Keywords: oxygen generating; oxygen; generating microparticles; tissue engineering ... See more keywords
Inhibition of melanoma using a nanoceria-based prolonged oxygen-generating phototherapy hydrogel
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1126094
Abstract: Tumor hypoxic environment is an inevitable obstacle for photodynamic therapy (PDT) of melanoma. Herein, a multifunctional oxygen-generating hydrogel loaded with hyaluronic acid-chlorin e6 modified nanoceria and calcium peroxide (Gel-HCeC-CaO2) was developed for the phototherapy of… read more here.
Keywords: melanoma; hydrogel; prolonged oxygen; phototherapy ... See more keywords
Oxygen-generating Hybrid Polymeric Nanoparticles with Encapsulated Doxorubicin and Chlorin e6 for Trimodal Imaging-Guided Combined Chemo-Photodynamic Therapy
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DOI: 10.7150/thno.22989
Abstract: The combination of chemotherapy with photodynamic therapy (PDT) has attracted broad attention as it can overcome limitations of conventional chemo-treatment by using different modes of action. However, the efficacy of PDT to treat solid tumors… read more here.
Keywords: photodynamic therapy; chemo; combined chemo; oxygen generating ... See more keywords