Bioengineered 3D Tissue Model of Intestine Epithelium with Oxygen Gradients to Sustain Human Gut Microbiome
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200447
Abstract: The human gut microbiome is crucial to hosting physiology and health. Therefore, stable in vitro coculture of primary human intestinal cells with a microbiome community is essential for understanding intestinal disease progression and revealing novel… read more here.
Keywords: epithelium; oxygen gradients; oxygen; gut microbiome ... See more keywords
Luminescent Nanosensors for Ratiometric Monitoring of Three-Dimensional Oxygen Gradients in Laboratory and Clinical Pseudomonas aeruginosa Biofilms
Sign Up to like & getrecommendations! Published in 2019 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.01116-19
Abstract: Biofilm infections are more difficult to treat than planktonic infections for a variety of reasons, such as decreased antibiotic penetration. Their complex structure makes biofilms challenging to study without disruption. To address this limitation, we… read more here.
Keywords: spatial temporal; dimensional oxygen; oxygen gradients; three dimensional ... See more keywords
Abstract B61: Intratumoral oxygen gradients mediate sarcoma cell invasion
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DOI: 10.1158/1538-7445.epso16-b61
Abstract: Hypoxia is a critical factor in the progression and metastasis of many cancers including soft tissue sarcomas. Frequently, oxygen (O2) gradients develop in tumors as they grow beyond their vascular supply leading to heterogeneous areas… read more here.
Keywords: invasion; sarcoma cell; cell invasion; oxygen gradients ... See more keywords
Study Hypoxic Response under Cyclic Oxygen Gradients Generated in Microfluidic Devices Using Real-Time Fluorescence Imaging
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DOI: 10.3390/bios12111031
Abstract: Oxygen plays important roles in regulating various biological activities under physiological and pathological conditions. However, the response of cells facing temporal variation in oxygen microenvironments has seldom been studied due to technical limitations. In this… read more here.
Keywords: oxygen gradients; cyclic oxygen; real time; oxygen ... See more keywords