Rational Engineering of the Nonheme Iron- and 2-Oxoglutarate-Dependent Oxygenase SptF.
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DOI: 10.1021/acs.orglett.2c00409
Abstract: The Fe- and 2-oxoglutarate-dependent oxygenase SptF is a promising powerful biocatalys with unusual catalytic versatility and promiscuity. The site-specific random substitution of N150, I63, and N65, which are involved in substrate interactions, generated three compounds… read more here.
Keywords: engineering; dependent oxygenase; oxoglutarate dependent; oxygenase sptf ... See more keywords