Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKT pathway
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DOI: 10.1007/s10616-017-0153-9
Abstract: Oxymatrine extracted from Sophora flavescens Ait as a natural polyphenolic phytochemical has been demonstrated to exhibit anti-tumor effects on various cancers, including Gallbladder carcinoma (GBC). However, its underlying mechanisms of function are largely unknown in… read more here.
Keywords: gbc cells; akt; pi3k akt; gallbladder carcinoma ... See more keywords
Oxymatrine attenuates cognitive deficits through SIRT1-mediated autophagy in ischemic stroke
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DOI: 10.1016/j.jneuroim.2018.06.018
Abstract: To investigate if oxymatrine could ameliorate hippocampus ischemia/reperfusion (I/R) injury induced in rats and explore the possible mechanism. Rats were randomly divided into four groups: sham group, I/R group, I/R + OMT-treated group, I/R + Vehicle-treated group. Oxymatrine or… read more here.
Keywords: oxymatrine attenuates; cognitive deficits; group; expression ... See more keywords
Oxymatrine protects against the effects of cardiopulmonary resuscitation via modulation of the TGF-β1/Smad3 signaling pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular medicine reports"
DOI: 10.3892/mmr.2018.8373
Abstract: Previous studies have demonstrated that oxymatrine may inhibit ventricular remodeling and serves an important role in the treatment of cardiovascular disease. The present study investigated whether oxymatrine treatment protects against the effects of cardiopulmonary resuscitation… read more here.
Keywords: treatment; protects effects; effects cardiopulmonary; signaling pathway ... See more keywords