Study of oxyresveratrol complexes with insoluble cyclodextrin based nanosponges: Developing a novel way to obtain their complexation constants and application in an anticancer study.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2019.115763
Abstract: The complexation of the bioactive compound oxyresveratrol (OXY) with a polymer called cyclodextrin-based nanosponge (CD-NS) and its application was studied.A new methodology is used to calculate, an apparent inclusion complex constant (KFapp) between a ligand… read more here.
Keywords: oxyresveratrol complexes; complexation; application; study oxyresveratrol ... See more keywords
Biochemical and histopathological analysis after sub-chronic administration of oxyresveratrol in Wistar rats.
Sign Up to like & getrecommendations! Published in 2021 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2021.2015243
Abstract: Oxyresveratrol (OXY) is a naturally occurring phenolic compound; however, there are no toxicity studies reported on its long term use. The aim of our work was to demonstrate the evaluation of acute and sub-chronic toxicity… read more here.
Keywords: chronic administration; sub chronic; wistar rats; oxyresveratrol ... See more keywords
Inhibition of Streptococcus mutans Biofilm Formation by the Joint Action of Oxyresveratrol and Lactobacillus casei
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DOI: 10.1128/aem.02436-21
Abstract: The homeostatic imbalance in dental plaque associated with a sharp increase in the number of cariogenic bacteria such as Streptococcus mutans is critical for the occurrence and development of caries. Probiotic therapy can restore ecological… read more here.
Keywords: oxyresveratrol; joint action; lactobacillus casei; action ... See more keywords
Resveratrol Demonstrated Higher Antiproliferative and Antiangiogenic Efficacy Compared with Oxyresveratrol on Head and Neck Squamous Cell Carcinoma Cell Lines
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DOI: 10.1177/1934578x1701201134
Abstract: Resveratrol and its derivative, oxyresveratrol, have various pharmacological effects. Several studies demonstrated the anticancer activity of resveratrol. However, little is known about the anticancer activity of oxyresveratrol. In this study, we compared the antiproliferative and… read more here.
Keywords: neck squamous; resveratrol; cell; antiproliferative antiangiogenic ... See more keywords
Neuroprotective Effect of Oxyresveratrol in Rotenone-Induced Parkinsonism Rats
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DOI: 10.1177/1934578x20966199
Abstract: Oxyresveratrol, a polyphenolic compound, has been reported as having antioxidant and anti-inflammatory effects. This study determined the neuroprotective effects of oxyresveratrol, extracted from the heartwood of Artocarpus lakoocha Roxburgh (Moraceae), on parkinsonism induced by rotenone.… read more here.
Keywords: oxyresveratrol; rotenone; neuroprotective effect; parkinsonism ... See more keywords
Anti-Inflammatory Activity of Oxyresveratrol Tetraacetate, an Ester Prodrug of Oxyresveratrol, on Lipopolysaccharide-Stimulated RAW264.7 Macrophage Cells
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DOI: 10.3390/molecules27123922
Abstract: Oxyresveratrol (OXY) has been reported for its anti-inflammatory activity; however, the pharmaceutical applications of this compound are limited by its physicochemical properties and poor pharmacokinetic profiles. The use of an ester prodrug is a promising… read more here.
Keywords: oxy tac; ester; anti inflammatory; prodrug ... See more keywords
Oxyresveratrol Inhibits TNF-α-Stimulated Cell Proliferation in Human Immortalized Keratinocytes (HaCaT) by Suppressing AKT Activation
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14010063
Abstract: Psoriasis is a complex inflammatory disease characterized by hyperproliferative keratinocyte caused by active PI3K/AKT signaling. TNF-α concentrated in the psoriatic lesions stimulates AKT activation. We previously discovered that oxyresveratrol inhibited inflammation via suppressing AKT phosphorylation,… read more here.
Keywords: akt activation; activation; tnf stimulated; oxyresveratrol ... See more keywords