Oxytocin and Animal Models for Autism Spectrum Disorder.
Sign Up to like & getrecommendations! Published in 2018 at "Current topics in behavioral neurosciences"
DOI: 10.1007/7854_2017_15
Abstract: Autism spectrum disorder (ASD) is a group of complex neurodevelopmental conditions characterized by deficits in social communication and by repetitive and stereotypic patterns of behaviors, with no pharmacological treatments available to treat these core symptoms.… read more here.
Keywords: system; spectrum disorder; animal models; autism spectrum ... See more keywords
The Importance of Experimental Investigation of the Peripheral Oxytocin System.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1759-5_1
Abstract: Oxytocin and oxytocin receptors are synthesized in the periphery where paracrine/autocrine actions have been described alongside endocrine actions effected by central release of oxytocin from the posterior pituitary. In the female reproductive system, classical actions… read more here.
Keywords: importance experimental; system; experimental investigation; peripheral oxytocin ... See more keywords
Mechanism of Natriuretic Effect of Oxytocin
Sign Up to like & getrecommendations! Published in 2020 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-020-04768-y
Abstract: In rats, intramuscular injection of oxytocin (0.25 nmol/100 g body weight) increased sodium excretion from 19±5 to 120±11 μmol/min. A significant correlation ( p read more here.
Keywords: mechanism natriuretic; biology; effect oxytocin; natriuretic effect ... See more keywords
Oxytocin reverses Aβ-induced impairment of hippocampal synaptic plasticity in mice.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.04.046
Abstract: AIM Oxytocin, a peptide hormone synthesized in the hypothalamic paraventricular nucleus, has been reported to participate in the regulation of learning and memory performance. However, no report has demonstrated the effect of oxytocin on the… read more here.
Keywords: induced impairment; synaptic plasticity; plasticity mice; plasticity ... See more keywords
Oxytocin induces intracellular Ca2+ release in cardiac fibroblasts from neonatal rats.
Sign Up to like & getrecommendations! Published in 2019 at "Cell calcium"
DOI: 10.1016/j.ceca.2019.102099
Abstract: Pituitary neuropeptide oxytocin is increasingly recognised as a cardiovascular hormone, in addition to its many regulatory roles in other organ systems. Studies in atrial and ventricular myocytes from the neonatal and adult rats have identified… read more here.
Keywords: oxytocin induces; oxytocin; cardiac fibroblasts; intracellular ca2 ... See more keywords
Oxytocin moderates risky decision-making during the Iowa Gambling Task: A new insight based on the role of oxytocin receptor gene polymorphisms and interventional cognitive study
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2019.134328
Abstract: The oxytocinergic system influences attentional bias towards emotional cues and feedback-based learning. Considering a tag single-nucleotide polymorphism (SNP) found through analysis of an intronic haplotype in the oxytocin receptor (OXTR) gene, we investigated the effect… read more here.
Keywords: decision making; gene; oxytocin receptor; oxtr gene ... See more keywords
Oxytocin Mobilizes Midbrain Dopamine toward Sociality
Sign Up to like & getrecommendations! Published in 2017 at "Neuron"
DOI: 10.1016/j.neuron.2017.07.002
Abstract: Oxytocin and dopamine possess significant overlap in the modulation of life-essential behaviors. Here, Xiao et al. (2017) show that the activity of dopamine neurons of the ventral tegmental area and the substantia nigra is finely tuned… read more here.
Keywords: midbrain dopamine; dopamine toward; oxytocin; mobilizes midbrain ... See more keywords
Chronic central oxytocin infusion impairs sociability in mandarin voles
Sign Up to like & getrecommendations! Published in 2017 at "Pharmacology Biochemistry and Behavior"
DOI: 10.1016/j.pbb.2017.09.006
Abstract: ABSTRACT Oxytocin (OT) has been reported to increase social contact, however some studies have related OT to reduced social contact, particularly with unfamiliar individuals. The underlying mechanisms of OT on social contact remain unclear. In… read more here.
Keywords: chronic central; central infusion; infusion; treatment ... See more keywords
Oxytocin mediated cardioprotection is independent of coronary endothelial function in rats
Sign Up to like & getrecommendations! Published in 2020 at "Peptides"
DOI: 10.1016/j.peptides.2020.170333
Abstract: The cardioprotective effect of oxytocin (OT) has been well established. However, there are no related studies on the role of endothelia in oxytocin-induced cardioprotection. Endothelial dysfunction (ED) model was established by injection of 0.01% Triton… read more here.
Keywords: endothelial function; microscopy; coronary endothelial; injury ... See more keywords
Anandamide regulates oxytocin/oxytocin receptor system in human placenta at term.
Sign Up to like & getrecommendations! Published in 2020 at "Placenta"
DOI: 10.1016/j.placenta.2020.02.012
Abstract: Oxytocin plays a pivotal role in the regulation of human parturition, however its role and modulation in the placenta is not fully understood. Non-labour cesarean section placentas were cultured with the endocannabinoid anandamide. We observed… read more here.
Keywords: placenta term; oxytocin receptor; system; oxytocin ... See more keywords
Oxytocin effects on the cognition of women with postpartum depression: A randomized, placebo-controlled clinical trial
Sign Up to like & getrecommendations! Published in 2021 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2020.110098
Abstract: BACKGROUND One of the most common mental disorders in the perinatal period is postpartum depression (PPD), which is associated with impaired emotional functioning due to alterations in different cognitive aspects including thought and facial emotion… read more here.
Keywords: postpartum depression; negative thoughts; placebo controlled; ppd ... See more keywords