Depression in early adolescence: Contributions from relational aggression and variation in the oxytocin receptor gene
Sign Up to like & getrecommendations! Published in 2018 at "Aggressive Behavior"
DOI: 10.1002/ab.21724
Abstract: Interpersonal stress arising from relational aggression (RA)-the intentional effort to harm others via rejection and exclusion-may increase risk for depression in youth. Biological vulnerabilities related to the hormone oxytocin, which affects social behavior and stress… read more here.
Keywords: receptor gene; relational aggression; depression; oxytocin receptor ... See more keywords
Oxytocin receptors are widely distributed in the prairie vole (Microtus ochrogaster) brain: Relation to social behavior, genetic polymorphisms, and the dopamine system
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25382
Abstract: Oxytocin regulates social behavior via direct modulation of neurons, regulation of neural network activity, and interaction with other neurotransmitter systems. The behavioral effects of oxytocin signaling are determined by the species‐specific distribution of brain oxytocin… read more here.
Keywords: brain; social behavior; oxytocin receptors; prairie vole ... See more keywords
Childhood adversity and parenting behavior: the role of oxytocin receptor gene polymorphisms
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-019-02009-9
Abstract: Previous research revealed experiences of childhood adversity (CA) to be related to less favorable parenting behavior. It can further be expected that maternal oxytocin receptor (OXTR) genes may influence parenting behavior and moderate relationships between… read more here.
Keywords: childhood adversity; parenting behavior; gene; oxytocin receptor ... See more keywords
Drug delivery to the human and mouse uterus using immunoliposomes targeted to the oxytocin receptor
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Obstetrics and Gynecology"
DOI: 10.1016/j.ajog.2016.08.027
Abstract: Background: The ability to provide safe and effective pharmacotherapy during obstetric complications, such as preterm labor or postpartum hemorrhage, is hampered by the systemic toxicity of therapeutic agents leading to adverse side effects in the… read more here.
Keywords: drug delivery; receptor targeted; targeted liposomes; receptor ... See more keywords
Oxytocin receptor and G-protein polymorphisms in patients with depression and separation anxiety.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2017.03.056
Abstract: BACKGROUND The impact of combined variants of Oxytocin Receptor (OXTR) and G protein β3 subunit genes was investigated in relation to retrospective reports of childhood as well as contemporary adult separation anxiety (SA), based on… read more here.
Keywords: depression; separation anxiety; childhood; anxiety ... See more keywords
Oxytocin moderates risky decision-making during the Iowa Gambling Task: A new insight based on the role of oxytocin receptor gene polymorphisms and interventional cognitive study
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2019.134328
Abstract: The oxytocinergic system influences attentional bias towards emotional cues and feedback-based learning. Considering a tag single-nucleotide polymorphism (SNP) found through analysis of an intronic haplotype in the oxytocin receptor (OXTR) gene, we investigated the effect… read more here.
Keywords: decision making; gene; oxytocin receptor; oxtr gene ... See more keywords
A Novel Link between the Oxytocin Receptor Gene and Impulsivity
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2020.07.033
Abstract: Impulsivity includes hasty actions, social intrusiveness or premature decision-making. Neuropeptides like oxytocin alleviate haste and anxiety, and affect fear conditioning. However, no investigations have been done via gene-network based approach with cognitive and interventional genetic… read more here.
Keywords: impulsive behavior; gene; oxytocin receptor; impulsivity ... See more keywords
Anandamide regulates oxytocin/oxytocin receptor system in human placenta at term.
Sign Up to like & getrecommendations! Published in 2020 at "Placenta"
DOI: 10.1016/j.placenta.2020.02.012
Abstract: Oxytocin plays a pivotal role in the regulation of human parturition, however its role and modulation in the placenta is not fully understood. Non-labour cesarean section placentas were cultured with the endocannabinoid anandamide. We observed… read more here.
Keywords: placenta term; oxytocin receptor; system; oxytocin ... See more keywords
Oxytocin receptor gene (OXTR) DNA methylation is associated with autism and related social traits – A systematic review
Sign Up to like & getrecommendations! Published in 2021 at "Research in Autism Spectrum Disorders"
DOI: 10.1016/j.rasd.2021.101785
Abstract: Abstract There is emerging evidence implicating oxytocin receptor gene (OXTR) DNA methylation (DNAm) in social behaviour. This review investigated its association with autism spectrum disorder (ASD) characteristics and related social dimensions, both in individuals with… read more here.
Keywords: gene oxtr; receptor gene; autism; dna methylation ... See more keywords
Oxytocin receptor DNA methylation and alterations of brain volumes in maltreated children
Sign Up to like & getrecommendations! Published in 2019 at "Neuropsychopharmacology"
DOI: 10.1038/s41386-019-0414-8
Abstract: Although oxytocin (OXT) plays an important role in secure attachment formation with a primary caregiver, which is impaired in many children with childhood maltreatment (CM), epigenetic regulation in response to CM is a key factor… read more here.
Keywords: methylation; brain; left ofc; dna methylation ... See more keywords
The oxytocin receptor signalling system and breast cancer: a critical review
Sign Up to like & getrecommendations! Published in 2020 at "Oncogene"
DOI: 10.1038/s41388-020-01415-8
Abstract: Breast cancer is making up one-quarter of all new female cancer cases diagnosed worldwide. Breast cancer surgeries, radiation therapies, cytotoxic chemotherapies and targeted therapies have made significant progress and play a dominant role in breast… read more here.
Keywords: cancer; signalling system; oxytocin receptor; breast cancer ... See more keywords