Remineralization effects of self-assembling peptide P11 -4 associated with three materials on early enamel carious lesions: An in vitro study.
Sign Up to like & getrecommendations! Published in 2021 at "Microscopy research and technique"
DOI: 10.1002/jemt.23937
Abstract: The aim of this study was to assess the remineralization of enamel caries lesions using the self-assembling peptide P11 -4 associated with different materials. Artificial early enamel lesions were prepared on 154 primary teeth. The… read more here.
Keywords: p11; self assembling; microscopy; peptide p11 ... See more keywords
Randomised clinical trial investigating self-assembling peptide P11-4 in the treatment of early caries
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Oral Investigations"
DOI: 10.1007/s00784-019-02901-4
Abstract: ObjectivesThis prospective, randomised, split-mouth, clinical trial compared the efficacy of the self-assembling peptide P11-4 to fluoride varnish in the treatment of early buccal carious lesions.Materials and methodsSubjects presenting at least two clinically affected teeth were… read more here.
Keywords: p11; self assembling; peptide p11; treatment ... See more keywords
Neu‐P11, a novel MT1/MT2 agonist, reverses diabetes by suppressing the hypothalamic‐pituitary‐adrenal axis in rats
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2017.07.001
Abstract: &NA; Excessive glucocorticoid (GC) in type 2 diabetes mellitus (T2DM) reduces insulin sensitivity, impairs &bgr;‐cell function, increases gluconeogenesis and glycogenolysis, impairs glucose uptake and metabolism, and reduces the insulinotropic effects of glucagon‐like peptide 1. Melatonin,… read more here.
Keywords: mt1 mt2; neu p11; p11; axis ... See more keywords
Early life stress induces age-dependent epigenetic changes in p11 gene expression in male mice
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-89593-7
Abstract: Early life stress (ELS) causes long-lasting changes in gene expression through epigenetic mechanisms. However, little is known about the effects of ELS in adulthood, specifically across different age groups. In this study, the epigenetic modifications… read more here.
Keywords: methylation; p11; age; expression ... See more keywords