Murine leukemia virus p12 tethers the capsid-containing pre-integration complex to chromatin by binding directly to host nucleosomes in mitosis
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DOI: 10.1371/journal.ppat.1007117
Abstract: The murine leukaemia virus (MLV) Gag cleavage product, p12, is essential for both early and late steps in viral replication. The N-terminal domain of p12 binds directly to capsid (CA) and stabilises the mature viral… read more here.
Keywords: p12; p12 tethers; integration; chromatin ... See more keywords