Dephosphorylation of Y228 and Y217 and phosphorylation of Y335 in p120 catenin activate convergent extension during zebrafish gastrulation
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Dynamics"
DOI: 10.1002/dvdy.524
Abstract: The cadherinâassociated protein p120 catenin regulates convergent extension through interactions with cadherin proteins, Cdc42, and Rac1, as we previously showed in zebrafish (Danio rerio). Phosphorylation of p120 catenin changes the nature of its activity in… read more here.
Keywords: p120 catenin; phosphorylation; convergent extension; p120 ... See more keywords
P120 and E-cadherin: double-edged swords in tumor metastasis.
Sign Up to like & getrecommendations! Published in 2019 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2019.07.020
Abstract: Cell-cell adhesion by adherens junctions controls proliferation and cell polarization and is crucial to maintain epithelial architecture and homeostasis. Downregulation of two of the main components of adherens junctions, E-cadherin and p120, is an often… read more here.
Keywords: cadherin p120; metastasis; p120; p120 cadherin ... See more keywords
miR-223 promotes colon cancer by directly targeting p120 catenin
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19541
Abstract: microRNA (miRNA) dysregulation is frequently observed in colon cancer. Previous studies found that miR-223 is upregulated in colon cancer and functions as an oncogene. Conversely, p120 is often downregulated or even absent in colon cancer,… read more here.
Keywords: catenin; colon; p120; colon cancer ... See more keywords
Combining metabolite doping and metabolic engineering to improve 2-phenylethanol production by engineered cyanobacteria
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.1005960
Abstract: 2-Phenylethanol (2-PE) is a rose-scented aromatic compound, with broad application in cosmetic, pharmaceutical, food and beverage industries. Many plants naturally synthesize 2-PE via Shikimate Pathway, but its extraction is expensive and low-yielding. Consequently, most 2-PE… read more here.
Keywords: metabolic engineering; doping metabolic; strain; metabolite doping ... See more keywords