Dephosphorylation of Y228 and Y217 and phosphorylation of Y335 in p120 catenin activate convergent extension during zebrafish gastrulation
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Dynamics"
DOI: 10.1002/dvdy.524
Abstract: The cadherin‐associated protein p120 catenin regulates convergent extension through interactions with cadherin proteins, Cdc42, and Rac1, as we previously showed in zebrafish (Danio rerio). Phosphorylation of p120 catenin changes the nature of its activity in… read more here.
Keywords: p120 catenin; phosphorylation; convergent extension; p120 ... See more keywords
Divergent roles of p120‐catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen‐induced rat skin tumors
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22630
Abstract: The heterocyclic amine 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP) targets multiple organs for tumorigenesis in the rat, including the colon and the skin. PhIP‐induced skin tumors were subjected to mutation screening, which identified genetic changes in Hras (7/40, 17.5%)… read more here.
Keywords: catenin; skin tumors; p120 catenin; catenin isoforms ... See more keywords
P120-catenin dependent collective brain infiltration by glioma cell networks
Sign Up to like & getrecommendations! Published in 2020 at "Nature cell biology"
DOI: 10.1038/s41556-019-0443-x
Abstract: Diffuse brain infiltration by glioma cells causes detrimental disease progression, but its multicellular coordination is poorly understood. We show here that glioma cells infiltrate the brain collectively as multicellular networks. Contacts between moving glioma cells… read more here.
Keywords: glioma; infiltration; p120 catenin; brain ... See more keywords
Monoubiquitination of p120-catenin is essential for TGFβ-induced epithelial-mesenchymal transition and tumor metastasis
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.aay9819
Abstract: Monoubiquitination of p120-catenin controls adherens junction dissociation in TGFβ-induced EMT. Disassembly of intercellular junctions is a hallmark of epithelial-mesenchymal transition (EMT). However, how the junctions disassemble remains largely unknown. Here, we report that E3 ubiquitin… read more here.
Keywords: p120 catenin; monoubiquitination; catenin; tgf induced ... See more keywords
Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/2352360
Abstract: Background Oral submucous fibrosis (OSF) is a potentially malignant disease of the oral cavity. New molecular predictors are needed to identify the high risk of malignant transformation in potentially malignant oral lesions. Our purpose is… read more here.
Keywords: p120 catenin; catenin; overexpression ptprz1; phosphorylation ... See more keywords
Abstract 1876: Mechanism of tyrosine kinase inhibitors resistance and role of epithelial mesenchymal transition in NSCLC
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs18-1876
Abstract: EMT is a vital process in the development of metastasis and occurs when epithelial cells lose their polarized structure, by downregulation of adherens junction proteins, E-cadherin and Claudin1, located on the cell membrane. Cells with… read more here.
Keywords: catenin; p120 catenin; h358er cells; tyrosine kinase ... See more keywords
p120-catenin subfamily members have distinct as well as shared effects on dendrite morphology during neuron development in vitro
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2023.1151249
Abstract: Dendritic arborization is essential for proper neuronal connectivity and function. Conversely, abnormal dendrite morphology is associated with several neurological pathologies like Alzheimer’s disease and schizophrenia. Among major intrinsic mechanisms that determine the extent of the… read more here.
Keywords: dendrite morphology; expression; p120 catenin; catenin ... See more keywords