Restoration of sensitivity of a diverse set of drug‐resistant Staphylococcus clinical strains by bactericidal protein P128
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Microbiology"
DOI: 10.1099/jmm.0.000697
Abstract: Purpose. P128, a phage‐derived lysin, exerts antibacterial activity on staphylococci by cleaving the pentaglycine‐bridge of peptidoglycan. We sought to determine whether the presence of P128 could re‐sensitize drug‐resistant bacteria to antibiotics by virtue of its… read more here.
Keywords: combination; aureus cons; drug; drug resistant ... See more keywords
Efficient Killing of Planktonic and Biofilm-Embedded Coagulase-Negative Staphylococci by Bactericidal Protein P128
Sign Up to like & getrecommendations! Published in 2017 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.00457-17
Abstract: ABSTRACT Coagulase-negative staphylococci (CoNS) are the major causative agents of foreign-body-related infections, including catheter-related bloodstream infections. Because of the involvement of biofilms, foreign-body-related infections are difficult to treat. P128, a chimeric recombinant phage-derived ectolysin, has… read more here.
Keywords: coagulase negative; p128; negative staphylococci; bactericidal ... See more keywords