p16/Ki‐67 immunostaining in the triage of young women with LSIL, ASC‐US, and ASC‐H cytology
Sign Up to like & getrecommendations! Published in 2019 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.24339
Abstract: Dear Editor, Although human papillomavirus (HPV) testing has been implemented for primary cervical cancer screening in many countries, primary cytology screening with Pap test still remains the most widespread despite its lower sensitivity. HPV testing… read more here.
Keywords: asc cytology; p16; young women; p16 immunostaining ... See more keywords
Time trends in prevalence of p16 positivity and combined HPV/p16 positivity in a large cohort of Danish vulvar cancer patients
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Cancer"
DOI: 10.1002/ijc.34446
Abstract: Vulvar cancer is rare, but causes substantial morbidity in affected patients. A subset of vulvar cancers is caused by high‐risk human papillomavirus (hrHPV), which primarily exerts its oncogenic effect through upregulation of tumor suppressor protein… read more here.
Keywords: hrhpv; positivity; p16 positivity; prevalence ... See more keywords
Treatment failure patterns are similar between p16− and p16+ oropharyngeal squamous cell carcinomas
Sign Up to like & getrecommendations! Published in 2022 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.779
Abstract: The incidence of p16+ oropharyngeal squamous cell carcinoma (OPSCC) has been increasing. The notion that p16+ OPSCC has a propensity for atypical and disseminating metastasis has gained traction. We compared treatment failure patterns in p16+… read more here.
Keywords: failure patterns; oropharyngeal squamous; squamous cell; p16 ... See more keywords
Aberrant methylation‐induced dysfunction of p16 is associated with osteoblast activation caused by fluoride
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22655
Abstract: Chronic exposure to fluoride continues to be a public health problem worldwide, affecting thousands of people. Fluoride can cause abnormal proliferation and activation of osteoblast and osteoclast, leading to skeletal fluorosis that can cause pain… read more here.
Keywords: methylation; skeletal fluorosis; p16; activation ... See more keywords
Staging von Oropharynxkarzinomen
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DOI: 10.1007/s00106-018-0499-0
Abstract: ZusammenfassungHintergrundDie TNM-Klassifikation (TNM: Tumor, Nodus, Metastasen) wird regelmäßig entsprechend der Literatur sowie international abgestimmter Empfehlungen aktualisiert. Ausgeprägte Änderungen haben sich im Rahmen der 8. Auflage v. a. für Oropharynxkarzinome ergeben.Material und MethodenDie Änderungen sowie die praktische Anwendung… read more here.
Keywords: die; p16; tnm; von oropharynxkarzinomen ... See more keywords
Cancer stage and pack-years, but not p16 or HPV, are relevant for survival in hypopharyngeal and laryngeal squamous cell carcinomas
Sign Up to like & getrecommendations! Published in 2018 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-018-4997-1
Abstract: PurposeRecently, p16 has been included in the TNM guideline for oropharyngeal carcinomas. The role of HPV and p16 in hypopharyngeal and laryngeal carcinomas has not yet been established sufficiently.MethodsHundred and thirty-four patients with hypopharyngeal and… read more here.
Keywords: p16; hypopharyngeal laryngeal; hpv; carcinomas ... See more keywords
Expression of MDM2 and p16 in angiomyolipoma.
Sign Up to like & getrecommendations! Published in 2018 at "Human pathology"
DOI: 10.1016/j.humpath.2018.01.022
Abstract: Angiomyolipoma (AML) arises primarily from the kidney but may grow into the retroperitoneal space mimicking a primary retroperitoneal tumor. Fine needle aspiration (FNA) and core needle biopsy of AML, particularly the fat-predominant variant, may be… read more here.
Keywords: p16; mdm2; expression mdm2; lipoma ... See more keywords
Conjunctival nevi and melanoma: multiparametric immunohistochemical analysis, including p16, sox10, hmb45, and ki-67.
Sign Up to like & getrecommendations! Published in 2020 at "Human pathology"
DOI: 10.1016/j.humpath.2020.07.020
Abstract: The role of p16 in the diagnosis and prognosis of conjunctival melanocytic lesions in the context of other clinical and immunohistochemical parameters has not been systematically explored. This study was conducted to determine whether p16… read more here.
Keywords: melanoma; p16; conjunctival; hmb45 ... See more keywords
Cytological interpretation of p16 immunohistochemistry in head and neck carcinomas: does the choice of fixative matter?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Society of Cytopathology"
DOI: 10.1016/j.jasc.2020.09.012
Abstract: INTRODUCTION Fine-needle aspiration (FNA) of nodal metastases plays a key role in the diagnosis of oropharyngeal squamous cell carcinoma (OPSCC). Because of significant clinical implications of human papillomavirus (HPV)-related OPSCC, immunohistochemistry for p16 as a… read more here.
Keywords: p16; immunohistochemistry; ccb; cytoplasmic staining ... See more keywords
Surrogate markers for high-risk human papillomavirus infection in oral epithelial dysplasia: A comparison of p16, Ki-67, and ProExC.
Sign Up to like & getrecommendations! Published in 2019 at "Oral surgery, oral medicine, oral pathology and oral radiology"
DOI: 10.1016/j.oooo.2019.09.019
Abstract: OBJECTIVE The aim of this study was to determine the utility of surrogate markers of human papillomavirus (HPV) infection in the diagnosis of HPV-associated oral epithelial dysplasia (OED). STUDY DESIGN Twelve cases of oral dysplasia… read more here.
Keywords: epithelial dysplasia; p16; infection; surrogate markers ... See more keywords
Evaluation of p16INK4a immunocytology and human papillomavirus (HPV) genotyping triage after primary HPV cervical cancer screening on self-samples in China.
Sign Up to like & getrecommendations! Published in 2021 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2021.05.014
Abstract: OBJECTIVE Self-sampling for human papillomavirus (HPV) testing is an effective option to increase the cervical screening coverage. How to best triage HPV-positive self-samples remains controversial. Here, we evaluated the performance of a novel p16INK4a immunocytology… read more here.
Keywords: self samples; p16; hpv; hpv positive ... See more keywords