The combined application of urinary liquid‐based cytology with fluorescence in situ hybridization and p16/Ki‐67 dual immunostaining is valuable for improving the early diagnosis of upper tract urothelial carcinomas
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DOI: 10.1002/dc.23796
Abstract: To evaluate the diagnostic values of urine liquid‐based cytology (LBC), fluorescence in situ hybridization (FISH), and p16/Ki‐67 dual immunostaining in the detection of upper tract urothelial carcinomas (UTUCs). read more here.
Keywords: p16 dual; fluorescence situ; liquid based; based cytology ... See more keywords
P29 Predictive value of p16/Ki-67 dual-stained cytology for the progression of cervical dysplasia
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DOI: 10.1136/ijgc-2019-esgo.92
Abstract: Introduction/Background Dual immunocytochemistry for p16/Ki-67 has been reported as a useful biomarker to identify cells of underlying high-grade cervical intraepithelial neoplasia in the Papanicolaou (Pap) cytology. Regression rates for atypical squamous cells of undetermined significance… read more here.
Keywords: p16 dual; progression; stained cytology; cytology ... See more keywords
Comparative Assessment of p16/Ki-67 Dual Staining Technology for cervical cancer screening in women living with HIV (COMPASS-DUST)–Study protocol
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DOI: 10.1371/journal.pone.0278077
Abstract: The risk of progression of low-grade (CIN1) to high-grade cervical intraepithelial neoplasia (CIN2/3) is 3-5 times higher for women living with HIV (WLHIV) than for HIV-negative women. Evidence suggests that the current cervical cancer screening… read more here.
Keywords: cervical cancer; cancer screening; p16 dual; dual staining ... See more keywords
p16/Ki-67 Dual Staining Is a Reliable Biomarker for Risk Stratification for Patients With Borderline/Mild Cytology in Cervical Cancer Screening
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DOI: 10.21873/anticanres.15738
Abstract: Background/Aim: To evaluate p16/Ki-67 dual-staining performance for detection of cervical intraepithelial neoplasia grade 2 or worse (CIN2+) in the management of women with minor cervical abnormalities. Patients and Methods: All 759 enrolled patients were tested… read more here.
Keywords: p16 dual; dual staining; risk stratification; cytology ... See more keywords
Significance of Triple Detection of p16/ki-67 Dual-Staining, Liquid-Based Cytology and HR HPV Testing in Screening of Cervical Cancer: A Retrospective Study
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DOI: 10.3389/fonc.2022.915418
Abstract: In addition to liquid-based cytology (LBC) and HR HPV testing, p16/ki-67 dual-staining is another method for cervical cancer screening. The combination of any two methods can improve the accuracy of screening, but some cervical lesions… read more here.
Keywords: hpv; cytology; p16 dual; dual staining ... See more keywords
Meta-analysis on the performance of p16/Ki-67 dual immunostaining in detecting high-grade cervical intraepithelial neoplasm
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DOI: 10.4103/0973-1482.183216
Abstract: Aim: Although routine screening contributes to substantial reductions in cervical cancer morbidity and mortality, the low specificity of HPV detection and limited sensitivity of cervical cytology necessitates the application of more optimized markers, such as… read more here.
Keywords: dual immunostaining; meta analysis; p16 dual; sensitivity ... See more keywords