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Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28146
Abstract: Many tumorāsuppressor genes contain CpG islands in their promoter regions which raised the necessity of investigating the role of methylation in silencing these genes. We examined p16 methylation as a potential biomarker in the peripheral…
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Keywords:
methylation;
p16 promoter;
p16 methylation;
colorectal cancer ... See more keywords
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Published in 2017 at "Medicine"
DOI: 10.1097/md.0000000000008106
Abstract: Background: Loss of tumor suppressor gene p16 expression via promoter methylation has been reported in hepatocellular carcinoma (HCC). This meta-analysis was conducted to evaluate the correlation between p16 methylation and HCC. Additionally, we also analyzed…
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Keywords:
methylation;
hcc;
p16 methylation;
p16 ... See more keywords
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Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.683876
Abstract: Background P16 methylation is expected to be potential diagnostic and therapeutic targets for esophageal cancer (EC). The intratumoral heterogeneity (ITH) of EC has been mentioned but has not been quantitatively measured yet. We aimed to…
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Keywords:
pathological diagnosis;
biopsy;
p16 methylation;
p16 ... See more keywords