P169 Activated effector T cells co-expressing multiple inhibitory receptors are enriched in the tumor immune microenvironment of HGSOC expressing high and uniform WT-1 antigen
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DOI: 10.1136/ijgc-2019-esgo.230
Abstract: Introduction/Background In high grade serous ovarian cancer(HGSOC),the association between tumor-infiltrating lymphocytes(TILs)and survival suggests a role for T cell immune surveillance. Despite this, initial attempts with PD1 checkpoint blockade and adoptive T-cell therapy(ACT) had limited efficacy.… read more here.
Keywords: expression; antigen; tumor; inhibitory receptors ... See more keywords