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Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.698565
Abstract: T-cell dysfunction arising upon repeated antigen exposure prevents effective immunity and immunotherapy. Using various clinically and physiologically relevant systems, we show that a prominent feature of PD-1-expressing exhausted T cells is the development of cellular…
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Keywords:
p16ink4a regulates;
senescence expressing;
senescence;
cellular senescence ... See more keywords