Characterization and epitope mapping of a panel of monoclonal antibodies against HIV‐1 matrix protein
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1662
Abstract: The HIV‐1 Gag precursor protein (p55) is the main structural protein comprising the matrix (MA/p17), capsid (CA/p24), and nucleocapsid (NC/p7) proteins, and is uniquely responsible for virion assembly within the virus life cycle. The MA… read more here.
Keywords: protein; virion; monoclonal antibodies; panel monoclonal ... See more keywords
Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms
Sign Up to like & getrecommendations! Published in 2021 at "Cell Research"
DOI: 10.1038/s41422-021-00497-7
Abstract: Dear Editor, The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARSCoV-2) has resulted in an unprecedented public health crisis, galvanizing a global effort for rapidly developing new therapeutic strategies… read more here.
Keywords: h014; antibody; rbd; sars cov ... See more keywords
Randomised, phase I pharmacokinetic study of adalimumab biosimilar CT-P17 (40 mg/0.4 mL) by autoinjector and prefilled syringe in healthy subjects.
Sign Up to like & getrecommendations! Published in 2021 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.14850
Abstract: AIM To evaluate pharmacokinetic equivalence and preliminary safety of the adalimumab biosimilar CT-P17 administered via autoinjector (CT-P17 AI) or prefilled syringe (CT-P17 PFS) in healthy subjects. METHODS This phase I, open-label study (ClinicalTrials.gov: NCT04295356) randomised… read more here.
Keywords: p17 pfs; equivalence; p17 p17; pharmacokinetic equivalence ... See more keywords
Exploiting Natural Cross-reactivity between Human Immunodeficiency Virus (HIV)-1 p17 Protein and Anti-gp41 2F5 Antibody to Induce HIV-1 Neutralizing Responses In Vivo
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DOI: 10.3389/fimmu.2017.00770
Abstract: Anti-p17 antibodies are able to neutralize human immunodeficiency virus (HIV) entry in a mouse model. In this study, we identified a region of sequence similarity between the epitopes of anti-p17 neutralizing antibodies and anti-gp41 neutralizing… read more here.
Keywords: cross reactivity; 2f5 antibody; hiv; anti gp41 ... See more keywords
Identification and Functional Analyses of Host Proteins Interacting with the p17 Protein of Avian Reovirus
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DOI: 10.3390/v14050892
Abstract: Avian reovirus (ARV) causes viral arthritis, chronic respiratory diseases, retarded growth and malabsorption syndrome. However, the precise molecular mechanism remains unclear. Here, we report the host cellular proteins that interact with ARV p17 by yeast… read more here.
Keywords: avian reovirus; p17 protein; p17; host ... See more keywords
Arrest of Cell Cycle by Avian Reovirus p17 through Its Interaction with Bub3
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14112385
Abstract: Avian reoviruses (ARV) are a group of poultry pathogens that cause runting and stunting syndrome (RSS), a condition otherwise known as “frozen chicken”, which are characterized by dramatically delayed growth in broilers. It has been… read more here.
Keywords: cell; arrest; bub3; cell cycle ... See more keywords