Melatonin protects against nonylphenol caused pancreatic β-cells damage through MDM2-P53-P21 axis.
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology research"
DOI: 10.1093/toxres/tfac016
Abstract: Nonylphenol (NP) is an endocrine disrupting chemical, which widely exists in environment and can result in multiple system dysfunction. Pancreas as one of the most important organs is sensitive to NP, while the detail toxic… read more here.
Keywords: dysfunction; p53 p21; mdm2 p53; p21 axis ... See more keywords
HSP90-regulated CHIP/TRIM21/p21 Axis Involves in the Senescence of Osteosarcoma Cells.
Sign Up to like & getrecommendations! Published in 2023 at "Protein and peptide letters"
DOI: 10.2174/0929866530666230519101148
Abstract: AIMS Investigation of the molecular mechanism of tripartite motif 21 (TRIM21) in osteosarcoma (OS) would shed light on the understanding of the pathogenesis of OS. BACKGROUND OS is the most frequent malignant bone tumor with… read more here.
Keywords: trim21; expression; senescence; p21 axis ... See more keywords