Nuclear co-expression of p21 and p27 induced effective cell-cycle arrest in T24 cells treated with BCG
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DOI: 10.1007/s10616-018-0278-5
Abstract: A proposed mechanism underlying the effect of bacillus Calmette–Guérin (BCG) treatment for bladder cancer cells is as follows: BCG-induced crosslinking of cell-surface receptors results in the activation of signaling cascades, including cell-cycle regulators. However, the… read more here.
Keywords: p21 p27; nuclear expression; bcg; p27 ... See more keywords
Roles of 12-Lipoxygenase and Its Interaction with Angiotensin II on p21 and p27 Expression in Diabetic Nephropathy
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DOI: 10.1159/000496440
Abstract: Background: 12-Lipoxygenase (12-LO) and angiotensin II (Ang II) are involved in the development of diabetic renal hypertrophy, in which cyclin-kinase inhibitors, p21 and p27 play pivotal roles. Here, we study the effects of 12-LO and… read more here.
Keywords: protein expression; p21 p27; p27 expression; expression ... See more keywords
LncRNA-ANCR regulates the cell growth of osteosarcoma by interacting with EZH2 and affecting the expression of p21 and p27
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DOI: 10.1186/s13018-017-0599-7
Abstract: BackgroundOsteosarcoma (OS) is one of the most common malignant tumors developed in the bone. EZH2 has been found to play pivotal roles in the development of various cancers. LncRNA-ANCR (anti-differentiation ncRNA) has been reported to… read more here.
Keywords: lncrna ancr; p21 p27; expression; lncrna ... See more keywords