Acute HSF1 depletion induces cellular senescence through the MDM2-p53-p21 pathway in human diploid fibroblasts
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DOI: 10.1242/jcs.210724
Abstract: ABSTRACT Heat shock transcription factor 1 (HSF1) regulates the expression of a wide array of genes, controls the expression of heat shock proteins (HSPs) as well as cell growth. Although acute depletion of HSF1 induces… read more here.
Keywords: p53 p21; p21 pathway; mdm2; senescence ... See more keywords