The cyclin dependent kinase inhibitor p21Cip1/Waf1 is a therapeutic target in high-risk neuroblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.906194
Abstract: Platinum-based chemotherapies such as cisplatin are used as first-line treatment for the paediatric tumour neuroblastoma. Although the majority of neuroblastoma tumours respond to therapy, there is a high fraction of high-risk neuroblastoma patients that eventually… read more here.
Keywords: p21cip1 waf1; risk neuroblastoma; p21cip1; high risk ... See more keywords
Epigenetic Regulation of p21cip1/waf1 in Human Cancer
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DOI: 10.3390/cancers11091343
Abstract: p21cip1/waf1 is a central regulator of cell cycle control and survival. While mutations are rare, it is commonly dysregulated in several human cancers due to epigenetic mechanisms influencing its transcriptional control. These mechanisms include promoter… read more here.
Keywords: p21cip1 waf1; human cancer; waf1 human; p21cip1 ... See more keywords