Soybean β-conglycinin and catfish cutaneous mucous p22 glycoproteins deteriorate sporangial cell walls of Pseudoperonospora cubensis and suppress cucumber downy mildew.
Sign Up to like & getrecommendations! Published in 2021 at "Pest management science"
DOI: 10.1002/ps.6375
Abstract: BACKGROUND Cucumber plants suffer from a serious threatening disease, downy mildew, throughout the growing seasons irrespective of the weather temperature. The causal agent, Pseudoperonospora cubensis, tends to evolve rapidly upon sequential applications of chemical fungicides… read more here.
Keywords: cucumber; soybean conglycinin; cubensis; p22 ... See more keywords
Visualizing Infection Initiation of Bacteriophage P22 by Cryo-Electron Tomography
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1704
Abstract: For successful infection, bacteriophages must overcome multiple barriers in the bacterial cell envelope to translocate viral DNA and proteins into the host cell. However, the molecular mechanisms underlying the phage infection initiation remain poorly understood.… read more here.
Keywords: cryo electron; phage; infection; p22 ... See more keywords
Tunable In Vivo Colocalization of Enzymes within P22 Capsid-Based Nanoreactors.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.3c00971
Abstract: Virus-like particles (VLPs) derived from bacteriophage P22 have been explored as biomimetic catalytic compartments. In vivo colocalization of enzymes within P22 VLPs uses sequential fusion to the scaffold protein, resulting in equimolar concentrations of enzyme… read more here.
Keywords: vivo colocalization; colocalization enzymes; activity; enzymes within ... See more keywords
Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics.
Sign Up to like & getrecommendations! Published in 2022 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.2c00094
Abstract: On the basis of the knowledge that the proline-rich hot spot PPPRPP region of P(151)PSNPPPRPP(160), an oligopeptide derived from the cytosolic portion of p22phox (p22), binds to the single functional bis-SH3 domain of the regulatory… read more here.
Keywords: phox; triproline; p47; targeting nox2 ... See more keywords
Delayed In Vivo Encapsulation of Enzymes Alters the Catalytic Activity of Virus-Like Particle Nanoreactors.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00636
Abstract: Encapsulation of enzymes inside protein cage structures, mimicking protein-based organelle structures found in nature, has great potential for the development of new catalytic materials with enhanced properties. In vitro and in vivo methodologies have been… read more here.
Keywords: vivo encapsulation; encapsulation; activity; virus like ... See more keywords
Modular interior loading and exterior decoration of a virus-like particle.
Sign Up to like & getrecommendations! Published in 2017 at "Nanoscale"
DOI: 10.1039/c7nr03018e
Abstract: Virus-like particles (VLPs) derived from the bacteriophage P22 offer an interesting and malleable platform for encapsulation and multivalent presentation of cargo molecules. The packaging of cargo in P22 VLP is typically achieved through genetically enabled… read more here.
Keywords: protein; virus like; p22; scaffold protein ... See more keywords