The downregulation of NADPH oxidase Nox4 during hypoxia in hemangioendothelioma cells: a possible role of p22 phox on Nox4 protein stability
Sign Up to like & getrecommendations! Published in 2022 at "Free Radical Research"
DOI: 10.1080/10715762.2021.2009116
Abstract: Abstract NADPH oxidase (Nox) 4 produces H2O2 by forming a heterodimer with p22 phox and is involved in hemangioendothelioma development through monocyte chemoattractant protein-1 (MCP-1) upregulation. Here, we show that Nox4 protein levels were maintained… read more here.
Keywords: p22 phox; phox; nox4 protein; hemangioendothelioma cells ... See more keywords
Three novel mutations in CYBA among 22 Iranians with Chronic granulomatous disease
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DOI: 10.1111/iji.12336
Abstract: Chronic granulomatous disease (CGD) is a rare primary immunodeficiency caused by defect in one of the components of nicotinamide adenine dinucleotide phosphate (NADPH)‐oxidase enzyme. The enzyme is at least composed of membrane‐bound subunits gp91‐phox and… read more here.
Keywords: granulomatous disease; chronic granulomatous; p22 phox; novel mutations ... See more keywords
NOX Activation by Subunit Interaction and Underlying Mechanisms in Disease
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2016.00301
Abstract: Nicotinamide adenine dinucleotide phosphate (NAPDH) oxidase (NOX) is an enzyme complex with the sole function of producing superoxide anion and reactive oxygen species (ROS) at the expense of NADPH. Vital to the immune system as… read more here.
Keywords: p22 phox; nox; activation; interaction ... See more keywords