Flavonoids improve the stability and function of P23H rhodopsin slowing down the progression of retinitis pigmentosa in mice
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DOI: 10.1002/jnr.25021
Abstract: The balanced homeostasis of the G protein–coupled receptor (GPCR), rhodopsin (Rho), is required for vision. Misfolding mutations in Rho cause photoreceptor death, leading to retinitis pigmentosa (RP) and consequently blindness. With no cure currently available,… read more here.
Keywords: retinitis pigmentosa; function; p23h rho; stability ... See more keywords