TMOD-10. Mouse Models of H3.3K27M, G34R, and EZHIP Define Distinct Epigenetic Routes to Gliomagenesis
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DOI: 10.1093/neuonc/noaf201.1884
Abstract: Diffuse midline gliomas (DMGs) and posterior fossa group A (PFA) ependymomas are aggressive pediatric brain tumors. Most DMGs harbor histone H3.3K27M or G34R mutations, or exhibit EZHIP overexpression. With a median survival of just 9–15… read more here.
Keywords: ezhip; 3k27m g34r; g34r ezhip; p2a pdgf ... See more keywords