P2RX1-Involved Glycolytic Metabolism Supports Neutrophil Activation in Acute Pancreatitis
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DOI: 10.3389/fimmu.2020.549179
Abstract: Acute pancreatitis (AP) is characterized by disordered inflammation of the pancreas, and the underlying mechanisms remain unclear. Purinergic signaling plays crucial roles in initiating and amplifying inflammatory signals. Recent evidence reveals that targeting dysregulated purinergic… read more here.
Keywords: acute pancreatitis; p2rx1; neutrophil activation; glycolytic metabolism ... See more keywords
Targeting Purinergic Receptor P2RX1 Modulates Intestinal Microbiota and Alleviates Inflammation in Colitis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.696766
Abstract: Inflammatory bowel disease (IBD) remains one of the most prevalent gastrointestinal diseases worldwide. Purinergic signaling has emerged as a promising therapeutic target of inflammation-associated diseases. However, little is known about the specific roles of purinergic… read more here.
Keywords: p2rx1; inflammation; receptor p2rx1; colitis ... See more keywords