Sensory neuronal P2RX4 receptors controls BDNF signaling in inflammatory pain
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DOI: 10.1038/s41598-018-19301-5
Abstract: Chronic inflammatory and neuropathic pains are major public health concerns. Potential therapeutic targets include the ATP-gated purinergic receptors (P2RX) that contribute to these pathological types of pain in several different cell types. The purinergic receptors… read more here.
Keywords: p2rx4; sensory neuronal; inflammatory pain; chronic inflammatory ... See more keywords
Possible Roles for Purinergic Receptor P2RX4 in Breast and Prostate Cancers
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DOI: 10.3390/ijms26189043
Abstract: The purinergic receptor P2RX4 contributes to the malignant behavior of breast and prostate cancers. It is upregulated in these malignancies and promotes tumor progression through mechanisms involving EMT, autophagy, and the release of pro-malignant lysosomal… read more here.
Keywords: breast prostate; p2rx4; prostate cancers; purinergic receptor ... See more keywords