BAC transgenic mice to study the expression of P2X2 and P2Y1 receptors
Sign Up to like & getrecommendations! Published in 2021 at "Purinergic Signalling"
DOI: 10.1007/s11302-021-09792-9
Abstract: Extracellular purines are important signaling molecules involved in numerous physiological and pathological processes via the activation of P2 receptors. Information about the spatial and temporal P2 receptor (P2R) expression and its regulation remains crucial for… read more here.
Keywords: p2ry1 gene; bac transgenic; transgenic mice; expression ... See more keywords
Opposing Roles of Calcium and Intracellular ATP on Gating of the Purinergic P2X2 Receptor Channel
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19041161
Abstract: P2X2 receptors (P2X2R) exhibit a slow desensitization during the initial ATP application and a progressive, calcium-dependent increase in rates of desensitization during repetitive stimulation. This pattern is observed in whole-cell recordings from cells expressing recombinant… read more here.
Keywords: intracellular atp; calcium; desensitization; receptor ... See more keywords