Ionotropic P2X4 and P2X7 receptors in the regulation of ion transport across rat colon
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15928
Abstract: ATP plays an important role as an extracellular messenger acting via different types of purinoceptors. Whereas most of the actions of ATP at intestinal epithelia are thought to be mediated by metabotropic P2Y receptors, the… read more here.
Keywords: p2x7; transport across; p2x4 p2x7; p2x7 receptors ... See more keywords
P2X4 and P2X7 are essential players in basal T cell activity and Ca2+ signaling milliseconds after T cell activation
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DOI: 10.1126/sciadv.abl9770
Abstract: Initial T cell activation is triggered by the formation of highly dynamic, spatiotemporally restricted Ca2+ microdomains. Purinergic signaling is known to be involved in Ca2+ influx in T cells at later stages compared to the… read more here.
Keywords: cell; cell activation; p2x4 p2x7; ca2 microdomains ... See more keywords
Interaction of Purinergic P2X4 and P2X7 Receptor Subunits
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2017.00860
Abstract: P2X4 and P2X7 are members of the P2X receptor family, comprising seven isoforms (P2X1–P2X7) that form homo- and heterotrimeric non-specific cation channels gated by extracellular ATP. P2X4 and P2X7 are widely coexpressed, particularly in secretory… read more here.
Keywords: p2x7 subunits; p2x7; p2x4 p2x7; interaction ... See more keywords