Continued P2X7 activation leads to mitochondrial fission and compromising microglial phagocytosis after subarachnoid haemorrhage
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DOI: 10.1111/jnc.15712
Abstract: Subarachnoid haemorrhage (SAH) has a high rate of disability and mortality. Extremely damaging molecules, including adenosine triphosphate (ATP), are released from extravasated red blood cells and nerve cells, which activate microglia and induce sterile tissue… read more here.
Keywords: p2x7 activation; phagocytosis; microglial phagocytosis; mitochondrial fission ... See more keywords