ATP indirectly stimulates hippocampal CA1 and CA3 pyramidal neurons via the activation of neighboring P2X7 receptor-bearing astrocytes and NG2 glial cells, respectively
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DOI: 10.3389/fphar.2022.944541
Abstract: There is ongoing dispute on the question whether CNS neurons possess ATP-sensitive P2X7 receptors (Rs) or whether only non-neuronal cells bear this receptor-type and indirectly signal to the neighboring neurons. We genetically deleted P2X7Rs specifically… read more here.
Keywords: pyramidal neurons; p2x7rs; ca3 pyramidal; ca1 ca3 ... See more keywords