P2Y Receptors for Extracellular Nucleotides: Contributions to Cancer Progression and Therapeutic Implications.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2021.114406
Abstract: Purinergic receptors for extracellular nucleotides and nucleosides contribute to a vast array of cellular and tissue functions, including cell proliferation, intracellular and transmembrane ion flux, immunomodulation and thrombosis. In mammals, the purinergic receptor system is… read more here.
Keywords: extracellular nucleotides; receptors extracellular; cancer; p2y receptor ... See more keywords
Pharmacology of P2Y receptors.
Sign Up to like & getrecommendations! Published in 2019 at "Brain research bulletin"
DOI: 10.1016/j.brainresbull.2019.03.010
Abstract: P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular nucleotides. There are eight mammalian P2Y receptor subtypes divided into two subgroups (P2Y1, P2Y2, P2Y4, P2Y6, and P2Y11) and (P2Y12, P2Y13, and P2Y14). The P2Y receptors are… read more here.
Keywords: receptor; pharmacology; p2y12 receptors; p2y receptors ... See more keywords
P2Y receptors in neuropathic pain
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacology Biochemistry and Behavior"
DOI: 10.1016/j.pbb.2019.172788
Abstract: This review summarizes and evaluates the relationship between neuropathic pain and P2Y receptors from inception to 2019. Purinergic receptors have been well studied in recent years using various molecular biological methods. The main research objective… read more here.
Keywords: receptors neuropathic; review; neuropathic pain; pain ... See more keywords
P2Y Receptors in Bone - Anabolic, Catabolic, or Both?
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.818499
Abstract: P2Y receptors, including eight subtypes, are G protein-coupled receptors that can be activated by extracellular nucleotides. Nearly all P2Y receptors are expressed in bone cells, suggesting their involvements in bone physiology and pathology. However, their… read more here.
Keywords: p2y receptors; bone anabolic; physiology; anabolic catabolic ... See more keywords