Articles with "p2y1" as a keyword



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P2Y1 Receptors - Properties and Functional Activities.

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Published in 2017 at "Advances in experimental medicine and biology"

DOI: 10.1007/5584_2017_57

Abstract: In this chapter we try to show a comprehensive image of current knowledge of structure, activity and physiological role of the P2Y1 purinergic receptor. The structure, distribution and changes in the expression of this receptor… read more here.

Keywords: functional activities; p2y1; p2y1 receptors; properties functional ... See more keywords
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Diverse signalling of the platelet P2Y1 receptor leads to a dichotomy in platelet function

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Published in 2018 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2018.03.014

Abstract: Abstract Platelet P2Y1 receptor signalling via RhoGTPases is necessary for platelet‐dependent leukocyte recruitment, where no platelet aggregation is observed. We investigated signalling cascades involved in distinct P2Y1‐dependent platelet activities in vitro, using specific inhibitors for… read more here.

Keywords: aggregation; p2y1 receptor; p2y1; platelet p2y1 ... See more keywords

Upregulation of P2Y1 in neonatal nociceptors regulates heat and mechanical sensitization during cutaneous inflammation

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Published in 2017 at "Molecular Pain"

DOI: 10.1177/1744806917730255

Abstract: The upregulation of various channels and receptors classically linked to sensory transduction from the periphery tightly correspond with changes in the responsiveness of specific subpopulations of primary afferents to mechanical and heat stimulation of the… read more here.

Keywords: inflammation; p2y1; upregulation p2y1; cutaneous inflammation ... See more keywords