Pharmacology of P2Y receptors.
Sign Up to like & getrecommendations! Published in 2019 at "Brain research bulletin"
DOI: 10.1016/j.brainresbull.2019.03.010
Abstract: P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular nucleotides. There are eight mammalian P2Y receptor subtypes divided into two subgroups (P2Y1, P2Y2, P2Y4, P2Y6, and P2Y11) and (P2Y12, P2Y13, and P2Y14). The P2Y receptors are… read more here.
Keywords: receptor; pharmacology; p2y12 receptors; p2y receptors ... See more keywords
Nucleotide transmitters ATP and ADP mediate intercellular calcium wave communication via P2Y12/13 receptors among BV-2 microglia
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DOI: 10.1371/journal.pone.0183114
Abstract: Nerve injury is accompanied by a liberation of diverse nucleotides, some of which act as ‘find/eat-me’ signals in mediating neuron-glial interplay. Intercellular Ca2+ wave (ICW) communication is the main approach by which glial cells interact… read more here.
Keywords: communication; p2y12 receptors; atp adp; calcium ... See more keywords
ADP-Mediated Upregulation of Expression of CD62P on Human Platelets Is Critically Dependent on Co-Activation of P2Y1 and P2Y12 Receptors
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceuticals"
DOI: 10.3390/ph13120420
Abstract: This study probed the differential utilization of P2Y1 and P2Y12 receptors in mobilizing CD62P (P-selectin) from intracellular granules following activation of human platelets with adenosine 5′-diphosphate (ADP, 100 µmol·L−1) Platelet-rich plasma (PRP) was prepared from… read more here.
Keywords: p2y1 p2y12; p2y12 receptors; expression cd62p; cd62p ... See more keywords