Bone turnover is altered in transgenic rats overexpressing the P2Y2 purinergic receptor
Sign Up to like & getrecommendations! Published in 2017 at "Purinergic Signalling"
DOI: 10.1007/s11302-017-9582-3
Abstract: It is now widely recognized that purinergic signaling plays an important role in the regulation of bone remodeling. One receptor subtype, which has been suggested to be involved in this regulation, is the P2Y2 receptor… read more here.
Keywords: bone; p2y2r; rats overexpressing; receptor ... See more keywords
Modulation of P2Y2 receptors in bovine cumulus oocyte complexes: effects on intracellular calcium, zona hardening and developmental competence
Sign Up to like & getrecommendations! Published in 2020 at "Purinergic Signalling"
DOI: 10.1007/s11302-020-09690-6
Abstract: The improvement of cryopreserved oocyte survival is imperative for the preservation of female fertility. In this study, we investigate whether P2Y2 receptors (P2Y2R) can be directly implicated in calcium (Ca 2+ ) homeostasis misbalances observed… read more here.
Keywords: competence; p2y2 receptors; oocyte; p2y2r ... See more keywords
Endothelial Cell–Specific Deletion of P2Y2 Receptor Promotes Plaque Stability in Atherosclerosis-Susceptible ApoE-Null Mice
Sign Up to like & getrecommendations! Published in 2017 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.116.308561
Abstract: Objective— Nucleotide P2Y2 receptor (P2Y2R) contributes to vascular inflammation by increasing vascular cell adhesion molecule-1 expression in endothelial cells (EC), and global P2Y2R deficiency prevents fatty streak formation in apolipoprotein E null (ApoE−/−) mice. Because… read more here.
Keywords: p2y2r; p2y2 receptor; p2y2r deficiency; mice ... See more keywords
Blockade of the P2Y2 Receptor Attenuates Alcoholic Liver Inflammation by Targeting the EGFR-ERK1/2 Signaling Pathway
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DOI: 10.2147/dddt.s346376
Abstract: Purpose It is well known that inflammation plays a key role in complex pathological progressions of alcohol-associated liver disease (ALD). To date, effective therapy for ALD is lacking. P2Y2 receptor (P2Y2R), a G protein-coupled P2Y… read more here.
Keywords: p2y2r; inflammation; liver; egfr erk1 ... See more keywords
Upregulation of P2Y2R, Active uPA, and PAI-1 Are Essential Components of Hantavirus Cardiopulmonary Syndrome
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2018.00169
Abstract: Sin Nombre virus (SNV) causes hantavirus cardiopulmonary pulmonary syndrome (HCPS) with the loss of pulmonary vascular endothelial integrity, and pulmonary edema without causing cytopathic effects on the vascular endothelium. HCPS is associated primarily with a… read more here.
Keywords: hcps; pai; hantavirus cardiopulmonary; p2y2r ... See more keywords