Mechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13
Sign Up to like & getrecommendations! Published in 2018 at "Nature"
DOI: 10.1038/s41586-018-0281-1
Abstract: The maintenance of genome stability during mitosis is coordinated by the spindle assembly checkpoint (SAC) through its effector the mitotic checkpoint complex (MCC), an inhibitor of the anaphase-promoting complex (APC/C, also known as the cyclosome)1,2.… read more here.
Keywords: p31comet; mcc; atpase trip13; trip13 ... See more keywords
p31Comet Splice Variants Induce Distinct Spindle Assembly Checkpoint Dynamics due to Their Unique N-Termini
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DOI: 10.3390/ijms26073089
Abstract: The role of p31Comet in deactivating the spindle assembly checkpoint is well described in the literature; however, the data are all completed using Variant 2 of p31Comet. p31Comet is known to be expressed as two… read more here.
Keywords: p31comet; assembly checkpoint; spindle assembly; splice variants ... See more keywords